Optimization of the Healing Response

Genous Bio-Engineered Rstent

The critical role of endothelium in vascular homeostasis is often overlooked or misunderstood.

Endothelium: The ideal candidate for the reduction of restenosis must have the following characteristics:
  • regulates permeability


  • acts as a barrier to prevent thrombus formation


  • modulates smooth muscle cell growth


  • produces vasoactive compounds
  • anti-proliferative effects on smooth muscle cells


  • anti-migratory effects on smooth muscle cells


  • anti-inflammatory


  • anti-thrombotic


  • vasodilatory